A systematic review into the incidence, severity and duration of antidepressant withdrawal effects: Are guidelines evidence-based?

A 2018 systematic review of research about withdrawal from antidepressants, commissioned by the UK All Party Parliamentary Group for Prescribed Drug Dependence. It concludes that just over half of people who try to come off antidepressants experience withdrawal effects, and nearly half of those describe the withdrawal effects as severe. It shows that current national guidelines (eg NICE in UK, APA in USA)  guidelines grossly underestimate the prevalence, severity and duration of withdrawal from ADs.

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